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Growth & Development

331 - Biomarker Levels and Enamel Defect Associated with Chronic Kidney Disease

Friday, May 24, 2024
3:45 PM – 3:55 PM EST
Location: Exhibit Hall (back left corner of the hall, space 137)

    Presenting Author(s)

  • Brittney M. Halliburton, DDS

    Pediatric Dentistry Resident
    Saint Louis University Pediatric Dentistry
    Saint Louis University
    St. Louis, Missouri, United States

    • Program Director(s)

  • DS

    Dan Stoeckel, DDS

    Pediatric Dentistry Residency Program Director
    Saint louis University
    St. Louis, Missouri, United States

Abstract:Previous literature has substantiated claims that children and adolescents with chronic kidney disease (CKD) often present with dental anomalies such as enamel defects, caries experience, and calculus accumulation. Some studies have theorized that there are biological markers associated with CKD; however, not much is known about this topic. The aim of this observational correlation study is to determine if levels of BUN, Creatinine, Phosphorus, Calcium correlate with enamel defects such as demarcated opacity, diffuse opacity, hypoplasia or other defects.

Method: Patients from Cardinal Glennon Children's Hospital in the dialysis unit ages 6-17 with CKD were selected for this study. Patients will be screened by clinical exam to visually assess the enamel defects if present on 2 molar and/or premolars using the enamel defects index (modified developmental defects of enamel index [DDEI]). Biomarker data will be collected using a retrospective chart review for at least 3 readings that correlate closely with timing of tooth development.

Results: Final data pending.

Conclusion: Final data pending.

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