461 - Dental Management of the Neurofibromatosis Type 1: A Case Report

Introduction:  Neurofibromatosis 1 is a rare genetic disorder characterized by an increased risk of benign and malignant tumors and other physical and neurological manifestations. The most prevalent manifestations are multiple tumors of nerves and skin (neurofibromas), as well as areas of abnormal skin color (pigmentation) including light brown discolorations (café-au-lait spots) under the arms or in the abdominal region.

Case Report:  This presentation discusses a 5-year-old male patient referred to Tufts University School of Dental Medicine with a chief complaint of multiple caries. The patient’s medical history is Neurofibromatosis type 1. Current medication includes Amoxicillin and Melatonin. The patient has no known drug allergy. Extraoral examination revealed pigmented spots “café-au-lait” in the abdominal region. The clinical examination indicated Angle class III malocclusion and intra-oral swelling related to tooth #S. A full-mouth dental rehabilitation was performed under general anesthesia, with a six-month follow-up.

Identify Supporting Agency and Grant Number: