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Special Health Care Needs

515 - Osteogenesis Imperfecta: A Comprehensive Overview

Saturday, May 25, 2024
1:15 PM - 1:25 PM EST
Location: Exhibit Hall (back left corner of the hall, space 137)

    Presenting Author(s)

  • Ridila Khan, DDS

    Pediatric Dental Resident
    University of Michigan, Ann Arbor, MI
    University of Michigan
    Fenton, Michigan, United States

    • Research Mentor(s)

  • YY

    Yu-Ju Yang, DDS

    Dept of Child & Adolescent Dentistry, Mott Children's Health Center
    Flint, Michigan, United States

    • Program Director(s)

  • JB

    James R. Boynton, DDS, MS

    Professor
    University of Michigan- Ann Arbor
    Ann Arbor, Michigan, United States

Abstract: Osteogenesis Imperfecta (OI) is a rare genetic disorder characterized by bone fragility, joint hypermobility, and connective tissue abnormalities. This disorder, resulting from mutations in collagen-related genes, manifests in various types and severities. Dental implications are prominent, including dentinogenesis imperfecta, tooth abnormalities, and an increased risk of jaw fractures. Comprehensive and cautious dental care, emphasizing trauma minimization and bleeding risk reduction, is crucial. Routine dental procedures pose minimal risks, but vigilant monitoring and meticulous oral hygiene practices are essential. Ongoing research into gene therapies, stem cells, and advancements in dental materials contribute to enhancing the quality of life for individuals with OI.This case report highlights the interconnected challenges of OI and DI, emphasizing the importance of specialized dental care and ongoing research for improved patient outcomes.

Identify Supporting Agency and Grant Number: Research supported by University of Michigan, Ann Arbor and Mott Children's Health Center in Flint, Michigan.